Iyo metabolic process yemuviri wemunhu ndeye biological oxidation process, uye iyo okisijeni inodiwa mukugadzirisa metabolic inopinda muropa remunhu kuburikidza nekufema system, inosanganiswa nehemoglobin (Hb) mumasero matsvuku eropa kuita oxyhemoglobin (HbO2), uyezve. anochiendesa kunhengo dzese dzemuviri.Chikamu chemasero enyama chinoenda.
Kuzara kweokisijeni yeropa (SO2)chikamu chehuwandu hweoxyhemoglobin (HbO2) inosungwa neokisijeni muropa kusvika kuhuwandu hwehuwandu hwehemoglobin (Hb) inogona kusungwa, kureva, kuwanda kweokisijeni yeropa muropa.Iyo yakakosha physiology yekufema kutenderera parameter.Iyo inoshanda oxygen saturation ndiyo reshiyo yeHbO2 concentration kune HbO2 + Hb concentration, iyo yakasiyana nepercent ye oxygenated hemoglobin.Nokudaro, kutarisa arterial oxygen saturation (SaO2) inogona kufungidzira oksijeni yemapapu uye kukwanisa kwehemoglobin kutakura oksijeni.Yakajairika arterial blood oxygen saturation ndeye 98%, uye venous ropa i75%.
(Hb inomirira hemoglobin, hemoglobin, yakapfupikiswa Hb)
Kuyera nzira
Zvirwere zvakawanda zvekiriniki zvinokonzeresa kushaikwa kweokisijeni, izvo zvinokanganisa zvakananga metabolism yemaseru, uye kutyisidzira zvakanyanya hupenyu hwevanhu.Naizvozvo, chaiyo-nguva yekutarisa kweiyo arterial blood oxygen concentration kwakakosha zvikuru mukununurwa kwekiriniki.
Iyo yechinyakare yeropa oxygen saturation yekuyera nzira ndeyekutanga kuunganidza ropa kubva mumuviri wemunhu, uyezve kushandisa yeropa gasi analyzer ye electrochemical ongororo kuyera chidimbu kumanikidzwa kwe.ropa okisijeni PO2kuverenga ropa reoxygen saturation.Iyi nzira yakaoma uye haigone kuramba ichiongororwa.
Ikozvino kuyerwa nzira ndeyekushandisa amunwe sleeve photoelectric sensor.Pakuyera, unongoda kuisa sensor pamunwe wemunhu, shandisa chigunwe sechigadziko chakajeka chehemoglobin, uye shandisa mwenje dzvuku ine wavelength ye660 nm uye pedyo-infrared mwenje ine wavelength ye940 nm semwaranzi.Pinda panobva mwenje uye uyere kusimba kwekufambiswa kwechiedza kuburikidza nematishu mubhedha kuti uverenge huwandu hwehemoglobin uye kuzara kweokisijeni muropa.Chiridzwa chacho chinogona kuratidza kuzara kweokisijeni muropa remunhu, zvichipa chiridzwa chekuyeresa okisijeni yeropa inoenderera mberi yekiriniki.
Reference value uye zvinoreva
Zvinowanzodavirwa izvozvoSpO2haifanire kunge iri pasi pe94% kazhinji, uye iyo isingasviki 94% haina kukwana okisijeni.Dzimwe nyanzvi dzakaisa SpO2 <90% seyero ye hypoxemia, uye vanotenda kuti kana SpO2 yakakwira kupfuura 70%, iko kurongeka kunogona kusvika ± 2%, uye kana SpO2 yakaderera kupfuura 70%, panogona kunge paine zvikanganiso.Mukuita kwekiriniki, takafananidza kukosha kweSpO2 yevarwere vakati wandei vane arterial blood oxygen saturation value.Tinotenda kutiSpO2 kuverengainogona kuratidza kufema kwemurwere uye kuratidza shanduko ye arterialropa okisijenikusvika pamwero wakati.Mushure mekuvhiyiwa kwe thoracic, kunze kwezviitiko zvega ega apo zviratidzo zvechipatara uye maitiro hazvifananidzi, kuongororwa kwegesi yeropa kunodiwa.Kushandiswa kwechigadziro che pulse oximetry monitoring kunogona kupa zviratidzo zvine musoro zvekucherechedza kwekliniki yekuchinja kwechirwere, kudzivisa kudzokororwa kweropa sampling kune varwere uye kuderedza vanamukoti ' Basa rinofanirwa kusimudzira.Kliniki, inowanzopfuura 90%.Zvechokwadi, inoda kuva mumadhipatimendi akasiyana.
Kutonga, kukuvadza, uye kuraswa kwe hypoxia
Hypoxia kusaenzana pakati pekupihwa kweokisijeni yemuviri uye kushandiswa kweokisijeni, kureva kuti, tissue cell metabolism iri muchimiro che hypoxia.Kuti muviri une hypoxic kana kwete zvinoenderana nekuti huwandu hwekutakura okisijeni uye matura eokisijeni anogamuchirwa netishu imwe neimwe anogona kuzadzisa zvinodiwa zve aerobic metabolism.Kukuvadza kwe hypoxia kune hukama nedhigirii, chiyero uye nguva ye hypoxia.Yakanyanya hypoxemia ndicho chikonzero chinowanzokonzera rufu kubva kune anesthesia, inoverengera inenge 1/3 kusvika 2/3 yerufu kubva mukusungwa kwemoyo kana kukuvara kwakanyanya kwesero reuropi.
Muchipatara, chero PaO2 <80mmHg zvinoreva hypoxia, uye <60mmHg zvinoreva hypoxemia.PaO2 inonzi 50-60mmHg inonzi mild hypoxemia;PaO2 inonzi 30-49mmHg inonzi moderate hypoxemia;PaO2<30mmHg inonzi yakanyanya hypoxemia.Ropa remurwere reoxygen saturation pasi pekufema kwemapfupa, nasal cannula uye mask oxygenation yaingova 64-68% (inenge yakaenzana nePaO2 30mmHg), iyo yakanga yakaenzana ne hypoxemia yakaoma.
Hypoxia ine simba guru pamuviri.Zvakadai senge pesvedzero paCNS, chiropa uye kushanda kweitsvo.Chinhu chekutanga chinoitika mu hypoxia ndiko kukurumidza kukurumidza kwekurova kwemoyo, kuwedzera kwekurova kwemoyo uye kubuda kwemoyo, uye kutenderera kweropa kunobhadhara kushayikwa kwehuwandu hweokisijeni nehupamhi hune simba.Panguva imwecheteyo, kugoverazve kwekuyerera kweropa kunoitika, uye uropi uye tsinga dzeropa dzinowedzerwa zvakasarudzwa kuti ive nechokwadi chekupa ropa rakakwana.Zvisinei, mumamiriro ezvinhu akaoma e hypoxic, nekuda kwekuunganidza kwe subendocardial lactic acid, ATP synthesis inoderedzwa, uye myocardial inhibition inogadzirwa, zvichiita kuti bradycardia, pre-contraction, ropa uye kubuda kwemwoyo, pamwe ne ventricular fibrillation uye mamwe arrhythmias Kunyange. stop.
Mukuwedzera, hypoxia uye chirwere chemurwere pachake chinogona kuva nemigumisiro inokosha pahomeostasis yemurwere.
Nguva yekutumira: Oct-12-2020